Genetics of Dyslipidemia
نویسندگان
چکیده
Genetics of Dyslipidemia Diego García-Giustiniani1,2 and Ricardo Stein3,4,5 Health in Code1, La Coruña, Spain; Grupo de Investigación Cardiovascular de La Universidad de La Coruña, La Coruña, Spain2; Grupo de Pesquisa em Cardiologia do Exercício do Hospital de Clínicas de Porto Alegre3; Serviço de Cardiologia do Hospital de Clínicas de Porto Alegre – Universidade Federal do Rio Grande do Sul4; Vitta Centro de Bem Estar Físico5, Porto Alegre, RS – Brazil
منابع مشابه
Relationship between polymorphism of SOCS-3 and dyslipidemia in China Xinjiang Uygur.
We investigated the relationship between the polymorphism of SOCS-3 and dyslipidemia of people from Uygur in Xinjiang, China. This cross-sectional study included 1379 participants in a Hetian Xinjiang Uygur population who were 30-70 years of age and were not from interracial marriages of 3 generations; all subjects were genotyped (909 dyslipidemia subjects, 470 healthy subjects). Allele (P = 0....
متن کاملNot just genomewide association studies: rare variants in genes not identified through genomewide association studies also contribute to hypertriglyceridemia.
Dyslipidemia (elevated low-density lipoprotein or elevated triglycerides and low high-density lipoprotein) is an established risk factor for the development of atherosclerosis.1 Heritability estimates for plasma lipids range from 25% to 80% and family studies suggest that within the family, genetic effects are more important than environmental.2 In a minority of cases, dyslipidemia is the resul...
متن کاملNational Lipid Association Annual Summary of Clinical Lipidology 2015.
The National Lipid Association (NLA) Annual Summary of Clinical Lipidology 2015 is a summary of principles important to the patient-centered evaluation, management, and care of patients with dyslipidemia. This summary is intended to be a "living document," with future annual updates based on emerging science, clinical considerations, and new NLA Position and Consensus Statements. The goal is to...
متن کاملPrediction of Adult Dyslipidemia Using Genetic and Childhood Clinical Risk Factors: The Cardiovascular Risk in Young Finns Study.
BACKGROUND Dyslipidemia is a major modifiable risk factor for cardiovascular disease. We examined whether the addition of novel single-nucleotide polymorphisms for blood lipid levels enhances the prediction of adult dyslipidemia in comparison to childhood lipid measures. METHODS AND RESULTS Two thousand four hundred and twenty-two participants of the Cardiovascular Risk in Young Finns Study w...
متن کاملRelationship of the APOA5/A4/C3/A1 gene cluster and APOB gene polymorphisms with dyslipidemia.
We determined the alleles of ten single nucleotide poly-morphisms (SNPs) in the APOA5/A4/C3/A1 gene cluster and in APOB in Han Chinese from Xinjiang Shihezi, China using MALDI-TOF mass spectrometry, and explored the correlation between these SNPs and dyslipidemia through a case-control study design with 250 pa-tients and 250 normal controls. All SNPs except for APOA5 rs2072560 conformed to Hard...
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